| Day | Date | | Opponent | Score | | | Location | Venue | Attendance | Notes |
|---|
| Sun | 9/15/1929 | A | Green Bay Packers | 0-14 | L | | Green Bay, WI | City Stadium | 5000 | |
| Sun | 9/22/1929 | H | Chillicothe Eagles | 7-0 | W | | Portsmouth, OH | | 2500 | |
| Sun | 9/29/1929 | H | Middletown Armco Blues | 32-0 | W | | Portsmouth, OH | | 2500 | |
| Sun | 10/6/1929 | H | Detroit Tigers | 79-0 | W | | Portsmouth, OH | | | |
| Sun | 10/13/1929 | A | Ironton Tanks | 0-3 | L | | Ironton, OH | Beechwood Stadium | | |
| Sun | 10/20/1929 | A | Cincinnati National Guards | 6-6 | T | | Cincinnati, OH | Redland Field | 4000 | |
| Sun | 10/27/1929 | A | Ashland Armco Yellowjackets | 19-0 | W | | Ashland, KY | Armco Field | 6500 | |
| Sun | 11/3/1929 | A | Ironton Tanks | 20-0 | W | | Ironton, OH | Beechwood Stadium | 7206 | |
| Sun | 11/10/1929 | A | South Akron Awnings | 15-6 | W | | Akron, OH | League Park | 8000 | |
| Sun | 11/17/1929 | A | Middletown Armco Blues | 22-0 | W | | Middletown, OH | Armco Field | 1000 | |
| Sun | 11/24/1929 | H | Ironton Tanks | 38-0 | W | | Portsmouth, OH | | 3500 | |
| Thu | 11/28/1929 | H | Cincinnati National Guards | 25-0 | W | | Portsmouth, OH | | 2500 | |
| Sun | 12/1/1929 | H | Ashland Armco Yellowjackets | 19-0 | W | | Portsmouth, OH | | 4000 | |
| Sun | 12/8/1929 | H | Chillicothe Eagles | 30-7 | W | | Portsmouth, OH | | 2500 | |
| Sun | 12/15/1929 | H | Columbus Mendel Tailors | 44-0 | W | | Portsmouth, OH | | | |
| Sun | 12/15/1929 | H | Minneapolis Redjackets | | - | | Portsmouth, OH | Labold Field | | Canceled |
